IL-2: Secreted by Th1 cells. Stimulates growth of helper and cytotoxic T cells. Immunosuppressant drugs inhibit production of IL-2 (cyclosporin, tacrolimus). Stimulate T cells.
IL-3: Secreted by activated T cells. Supports the growth and differentiation of bone marrow stem cells. Has fucntion similar to GM-CSF. Stimulates bone marrow.
IL-4: Secreted by Th2 cells. Promotes growth of B cells. Enhances class switching to IgE and IgG. Induces generic T-helper cell to become Th2 cell. IL-4 stimulates IgE and IgG production.
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